Article
Fecal microbiota transplantation before hematopoietic stem cell transplantation in a pediatric case of chronic diarrhea with a FOXP3 mutation.
Pediatrics and neonatology - 1 Mar 2021
Wu Wenyan, Shen Nan, Luo Lijuan, Deng Zhaohui, Chen Jing, Tao Yue, Mo Xi, Cao Qing
Abstract excerpt
BACKGROUND: Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare disorder caused by mutation of the forkhead box protein 3 (FOXP3) gene, often leading to intractable and life-threatening diarrhea. Fecal microbiota transplantation (FMT), has been regarded in recent years as an available approach to reconstruct disrupted gut microbiome and successfully used to attenuates...
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