Article
Two nuclear localization signals regulate intracellular localization of the duck enteritis virus UL13 protein.
Poultry science - 1 Jan 2021
Yang Linjiang, Hu Xixia, Cheng Anchun, Wang Mingshu, Jia Renyong, Yang Qiao, Wu Ying, Chen Shun, Liu Mafeng, Zhu Dekang, Ou Xumin, Wen XingJian, Mao Sai, Sun Di, Zhang Shaqiu, Zhao Xinxin, Huang Juan, Gao Qun, Liu Yunya, Yu Yanling, Zhang Ling, Tian Bin, Pan Leichang, Chen Xiaoyue
Abstract excerpt
Duck enteritis virus (DEV) multifunctional tegument protein UL13 is predicted to be a conserved herpesvirus protein kinase; however, little is known about its subcellular localization signal. In this study, through transfection of 2 predicted nuclear signals of DEV UL13 fused to enhanced green fluorescent protein, 2 bipartite nuclear localization signals (NLS) were identified. We found that ivermectin blocked the...
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