Article
Genetic diversity of Trypanosoma cruzi parasites infecting dogs in southern Louisiana sheds light on parasite transmission cycles and serological diagnostic performance.
PLoS neglected tropical diseases - 1 Dec 2020
Dumonteil Eric, Elmayan Ardem, Majeau Alicia, Tu Weihong, Duhon Brandy, Marx Preston, Wolfson Wendy, Balsamo Garry, Herrera Claudia
Abstract excerpt
BACKGROUND: Chagas disease is a neglected zoonosis of growing concern in the southern US, caused by the parasite Trypanosoma cruzi. We genotyped parasites in a large cohort of PCR positive dogs to shed light on parasite transmission cycles and assess potential relationships between parasite diversity and serological test performance. METHODOLOGY/PRINCIPAL FINDINGS: We used a metabarcoding approach based on deep...
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