Article
Fifty years of cycling.
Molecular biology of the cell - 15 Dec 2020
Biggins Sue, Hartwell Lee, Toczyski David
Abstract excerpt
Fifty years ago, the first isolation of conditional budding yeast mutants that were defective in cell division was reported. Looking back, we now know that the analysis of these mutants revealed the molecular mechanisms and logic of the cell cycle, identified key regulatory enzymes that drive the cell cycle, elucidated structural components that underly essential cell cycle processes, and influenced our thinking...
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