Article
Genetic causes of haemophilia in women and girls.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Mar 2021
Miller Connie H, Bean Christopher J
Abstract excerpt
Women and girls reported as "haemophilic females" may have complex genetic causes for their haemophilia phenotype. In addition, women and girls may have excessive bleeding requiring treatment simply because they are heterozygous for haemophilia alleles. While severe and moderate haemophilia are rare in females, 16% of patients with mild haemophilia A and almost one-quarter of those with mild haemophilia B seen in...
Topics
- Factor IX
- Factor VIII
- Female
- Hemophilia A
- Hemophilia B
- Heterozygote
- Humans
- Phenotype