Article
Severe and moderate haemophilia A and B in US females.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Mar 2014
Di Michele D M, Gibb C, Lefkowitz J M, Ni Q, Gerber L M, Ganguly A
Abstract excerpt
Haemophilia A and B are rare X-lined hemorrhagic disorders that typically affect men. Women are usually asymptomatic carriers, but may be symptomatic and, rarely, also express severe (factor VIII (FVIII) or factor IX (FIX) <0.01 U mL(-1)) or moderately severe (FVIII/FIX 0.01-0.05 U mL(-1)) phenotypes. However, data on clinical manifestations, genotype and the psychosocial ramifications of illness in severely...
Topics
- Cytogenetic Analysis
- Factor IX
- Factor VIII
- Female
- Hemophilia A
- Hemophilia B
- Humans
- Male
- Mutation
- Phenotype
- Quality of Life
- Registries