Article
Establishment of Etv5 gene knockout mice as a recipient model for spermatogonial stem cell transplantation.
Biology open - 6 Jan 2021
Zhang Xianyu, Zhao Xin, Li Guoling, Zhang Mao, Xing Pingping, Li Zicong, Chen Bin, Yang Huaqiang, Wu Zhenfang
Abstract excerpt
Spermatogonial stem cell (SSC) transplantation is an alternative reproductive method to achieve conservation and production of elite animals in livestock production. Creating a recipient animal without endogenous germ cells is important for effective SSC transplantation. However, natural mutants with depletion of SSCs are difficult to obtain, and drug ablation of endogenous germ cells is arduous to perform for...
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