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Article

The circ_0004463/miR-380-3p/FOXO1 axis modulates mitochondrial respiration and bladder cancer cell apoptosis.

Cell cycle (Georgetown, Tex.) - 1 Dec 2020

Wu Shuiqing, Deng Huanghao, He Haiqing, Xu Ran, Wang Yinhuai, Zhu Xuan, Zhang Jinhua, Zeng Qi, Zhao Xiaokun

Abstract excerpt

Bladder cancer is one of the most commonly diagnosed and fatal malignancies of the urinary tract. Noncoding RNAs have been reported to be new biomarkers and effective treatment targets for bladder cancer. In the present study, we identified a novel bladder cancer-related circRNA-miRNA-mRNA network, the circ_0004463/miR-380-3p/FOXO1 axis. circ_0004463 is significantly downregulated, whereas miR-380-3p is...

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Identifiers

PMID: 33283616
DOI: 10.1080/15384101.2020.1852746
PMCID: PMC7781606

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