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Expression Regulation and Physiological Role of Transcription Factor FOXO3a During Ovarian Follicular Development

5 Nov 2020

Abstract excerpt

In mammals, developing ovarian follicles transform from primordial follicles to primary follicles, secondary follicles, and mature follicles, accompanied by changes in follicular secretory functions. FoxO3a is a member of the forkhead transcription factor family (FoxO), which plays an important role in the cell cycle, DNA damage repair, apoptosis, oxidative stress, and energy metabolism. Recent studies have shown...

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PMID: 33250784
DOI: 10.3389/fphys.2020.595086

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