Article
Histological characteristics of lung adenocarcinoma with uncommon actionable alterations: special emphasis on MET exon 14 skipping alterations.
Histopathology - 1 Jun 2021
Hayashi Takuo, Kohsaka Shinji, Takamochi Kazuya, Kishikawa Satsuki, Ikarashi Daiki, Sano Kei, Hara Kieko, Onagi Hiroko, Suehara Yoshiyuki, Takahashi Fumiyuki, Saito Tsuyoshi, Nakatsura Tetsuya, Kitano Shigehisa, Suzuki Kenji, Yao Takashi
Abstract excerpt
AIMS: In the evolving era of precision medicine, increasing emphasis is placed on detecting molecular alterations driving the development of specific cancers and targeting them with matched therapies that can yield the best outcomes for patients. Lung adenocarcinomas with uncommon actionable alterations, including MET exon 14 skipping (METex14), ERBB2 and BRAF mutations, are rare and poorly characterised cancers....
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