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Article

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi.

Nature communications - 22 Jul 2016

Chibucos Marcus C, Soliman Sameh, Gebremariam Teclegiorgis, Lee Hongkyu, Daugherty Sean, Orvis Joshua, Shetty Amol C, Crabtree Jonathan, Hazen Tracy H, Etienne Kizee A, Kumari Priti, O'Connor Timothy D, Rasko David A, Filler Scott G, Fraser Claire M, Lockhart Shawn R, Skory Christopher D, Ibrahim Ashraf S, Bruno Vincent M

Abstract excerpt

Mucormycosis is a life-threatening infection caused by Mucorales fungi. Here we sequence 30 fungal genomes, and perform transcriptomics with three representative Rhizopus and Mucor strains and with human airway epithelial cells during fungal invasion, to reveal key host and fungal determinants contributing to pathogenesis. Analysis of the host transcriptional response to Mucorales reveals platelet-derived growth...

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Identifiers

PMID: 27447865
DOI: 10.1038/ncomms12218
PMCID: PMC4961843

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PDGFRB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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