A Functional Polymorphism in HIF-3α Is Related to an Increased Risk of Ischemic Stroke.

doi:10.1007/s12031-020-01728-z

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A Functional Polymorphism in HIF-3α Is Related to an Increased Risk of Ischemic Stroke.

Journal of molecular neuroscience : MN - 1 May 2021

Gu Xi-Xi, Tang Zhuan-Zhi, He Yong-Ling, Zeng Zhi-Neng, Shi Wu-Xiang, Qiao Yong-Chao, Wei Ye-Sheng

Abstract excerpt

Hypoxia-inducible factor-3α (HIF-3α), a member of HIF family, can mediate adaptive responses to low oxygen and ischemia. It is believed that HIF plays crucial roles in stroke-related diseases. However, there are no reports on the association between HIF-3α genetic variants and ischemic stroke (IS) susceptibility. Therefore, we examined the association between HIF-3α gene polymorphisms (rs3826795, rs2235095, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged

Share to Apoptosis Regulatory Proteins

Share to Fatty Acids, Nonesterified

Share to Gene Frequency

Share to Homocysteine

Share to Ischemic Stroke

Share to Polymorphism, Single Nucleotide

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33226577
DOI: 10.1007/s12031-020-01728-z
PMCID: PMC8064973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Functional Polymorphism in HIF-3α Is Related to an Increased Risk of Ischemic Stroke.PMID 33226577Read ↗

Correlations between ATF3 polymorphisms and ischemic stroke in Dali, Yunnan Province, as determined by a case-control studySemantic proximity Read ↗

Identification of hypoxia-related genes and exploration of their relationship with immune cells in ischemic strokeSemantic proximity Read ↗

The Association Between the Genetic Variants of the NOTCH3 Gene and Ischemic Stroke Risk.Semantic proximity Read ↗

Network-pharmacology-based study on the mechanism of fibrates regulating HIF-1A in the treatment of ischemic strokeSemantic proximity Read ↗

Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysisSemantic proximity Read ↗

Circulating lncRNAs HIF1A-AS2 and LINLK-A: Role and Relation to Hypoxia-Inducible Factor-1α in Cerebral Stroke PatientsSemantic proximity Read ↗

[The HIF1a polymorphism is a diagnostic marker of ischemic stroke].Semantic proximity Read ↗

CYP3A4 and CYP11A1 Variants are Risk Factors for Ischemic Stroke: a Case Control StudySemantic proximity Read ↗

Influence of ZFHX3 Polymorphisms on the Risk of Ischemic Stroke in Chinese Han Population.Semantic proximity Read ↗

HIF3α: the little we know.Semantic proximity Read ↗

Evaluation of VEGFA gene variants for possible roles in cerebral infarction diseasesSemantic proximity Read ↗

Superoxide dismutase gene polymorphism is associated with ischemic stroke risk in the Chinese Han populationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.