Article
Small platelet microparticle levels are increased in pulmonary arterial hypertension.
European journal of clinical investigation - 1 Jan 2013
Nadaud Sophie, Poirier Odette, Girerd Barbara, Blanc Catherine, Montani David, Eyries Mélanie, Imbert-Bismut Françoise, Pacheco Antoine, Vigne Jacques, Tregouet David-Alexandre, Humbert Marc, Soubrier Florent
Abstract excerpt
BACKGROUND: The various aetiologies and risk factors for pulmonary arterial hypertension (PAH) lead to close phenotypes with small differences. Plasma microparticles have been shown to be increased in vascular pathologies including PAH. The aim of this study was to determine whether the levels of endothelial and platelet-derived microparticles could vary between different forms of PAH: idiopathic PAH (iPAH),...
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