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Article

Target Genetic Abnormalities for the Treatment of Colon Cancer and Its Progression to Metastasis.

Current drug targets - 1 Jan 2021

Baviskar Tushar, Momin Munira, Liu Jingwen, Guo Bin, Bhatt Lokesh

Abstract excerpt

Colorectal carcinogenesis involves various processes from the accumulation of genetic alterations to genetic and epigenetic modulations and chromosomal abnormalities. It also involves mutations in oncogenes and tumour suppressor genes. Genomic instability plays a vital role in CRC. Advances in modern biological techniques and molecular level studies have identified various genes involved in colorectal cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33213339
DOI: 10.2174/1389450121666201119141015

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