Article
Ssu72 Regulates Fungal Development, Aflatoxin Biosynthesis and Pathogenicity in Aspergillus flavus.
Toxins - 13 Nov 2020
Yang Guang, Cao Xiaohong, Qin Ling, Yan Lijuan, Hong Rongsheng, Yuan Jun, Wang Shihua
Abstract excerpt
The RNA polymerase II (Pol II) transcription process is coordinated by the reversible phosphorylation of its largest subunit-carboxy terminal domain (CTD). Ssu72 is identified as a CTD phosphatase with specificity for phosphorylation of Ser5 and Ser7 and plays critical roles in regulation of transcription cycle in eukaryotes. However, the biofunction of Ssu72 is still unknown in Aspergillus flavus, which is a...
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