Article
Epigenomics, genomics, resistome, mobilome, virulome and evolutionary phylogenomics of carbapenem-resistant Klebsiella pneumoniae clinical strains.
Microbial genomics - 1 Dec 2020
Kopotsa Katlego, Mbelle Nontombi M, Osei Sekyere John
Abstract excerpt
Carbapenem-resistant Klebsiella pneumoniae (CRKP) remains a major clinical pathogen and public health threat with few therapeutic options. The mobilome, resistome, methylome, virulome and phylogeography of CRKP in South Africa and globally were characterized. CRKP collected in 2018 were subjected...
Topics
- Anti-Bacterial Agents
- Carbapenem-Resistant Enterobacteriaceae
- Drug Resistance, Multiple, Bacterial
- Epigenomics
- Evolution, Molecular
- Female
- Humans
- Klebsiella Infections
- Klebsiella pneumoniae
- Male
- Mutation
- Phylogeny
- Plasmids
- Prophages
- South Africa
- Virulence Factors
- Whole Genome Sequencing