Article
HLA-A and HLA-DRB1 may play a unique role in ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis.
Reproductive biology and endocrinology : RB&E - 7 Nov 2020
Zhao Xiaoya, Li Juan, Zhu Qian, Liang Guiling, Xia Wei, He Xiaoqing, Zhu Chenfeng, Qi Hang, Deng Bo, Chen Xiangjun, Zhang Jian
Abstract excerpt
BACKGROUND: Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis (NMDAR-E) is a severe autoimmune neurological disorder, and the influence of teratoma-induced autoantibodies on the pathogenesis remains unclear. METHODS: Ovarian teratoma tissues were collected from teratoma patients with and without NMDAR-E. Proteins were extracted and then analyzed using iTRAQ-coupled LC-MS/MS, which was...
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