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Article

An extreme-phenotype genome-wide association study identifies candidate cannabinoid pathway genes in Cannabis.

Scientific reports - 29 Oct 2020

Welling Matthew T, Liu Lei, Kretzschmar Tobias, Mauleon Ramil, Ansari Omid, King Graham J

Abstract excerpt

Cannabis produces a class of isoprenylated resorcinyl polyketides known as cannabinoids, a subset of which are medically important and exclusive to this plant. The cannabinoid alkyl group is a critical structural feature that governs therapeutic activity. Genetic enhancement of the alkyl side-chain could lead to the development of novel chemical phenotypes (chemotypes) for pharmaceutical end-use. However, the...

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Identifiers

PMID: 33122674
DOI: 10.1038/s41598-020-75271-7
PMCID: PMC7596533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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