Article
Capture-based enrichment of Theileria parva DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional intra-specific genetic diversity.
PLoS neglected tropical diseases - 1 Oct 2020
Palmateer Nicholas C, Tretina Kyle, Orvis Joshua, Ifeonu Olukemi O, Crabtree Jonathan, Drabék Elliott, Pelle Roger, Awino Elias, Gotia Hanzel T, Munro James B, Tallon Luke, Morrison W Ivan, Daubenberger Claudia A, Nene Vish, Knowles Donald P, Bishop Richard P, Silva Joana C
Abstract excerpt
Theileria parva is an economically important, intracellular, tick-transmitted parasite of cattle. A live vaccine against the parasite is effective against challenge from cattle-transmissible T. parva but not against genotypes originating from the African Cape buffalo, a major wildlife reservoir, prompting the need to characterize genome-wide variation within and between cattle- and buffalo-associated T. parva...
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