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Predicted coverage by 4CMenB vaccine against invasive meningococcal disease cases in the Netherlands

20 Oct 2020

Abstract excerpt

Neisseria meningitidis serogroup B is a major cause of invasive meningococcal disease in Europe. In the absence of a conjugate serogroup B vaccine, a subcapsular 4CMenB vaccine was developed. Data on 4CMenB vaccine efficacy is still limited. Recently, genomic MATS (Meningococcal Antigen Typing System) was developed as a tool to predict strain coverage, using vaccine antigens sequence data. We characterized all...

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PMID: 33097311
DOI: 10.1016/j.vaccine.2020.10.008

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