Article
An evaluation of olaparib for the treatment of pancreatic cancer.
Expert opinion on pharmacotherapy - 1 Mar 2021
Vaishampayan Ulka N
Abstract excerpt
INTRODUCTION: Advanced pancreatic cancer remains a lethal, incurable malignancy. Chemotherapy is the mainstay of systemic therapy consideration in metastatic pancreas cancer. Homologous recombinant DNA repair mutations are reported in about 7% of pancreas cancer cases and have rapidly emerged as actionable mutations. AREAS COVERED: A review was conducted of publications of PARP inhibitors in pancreatic...
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