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Phenylalanine Effects on Brain Function in Adult Phenylketonuria

22 Oct 2020

Abstract excerpt

Objective To evaluate the relationship between circulating phenylalanine and brain function as well as neuropsychiatric symptoms in adults with phenylketonuria. Methods In this prospective cross-sectional study, early-treated patients with phenylketonuria older than 30 years and age- and sex-matched controls were included. Extensive neurologic evaluation, neuropsychological and behavioral testing, sensory and...

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PMID: 33093221
DOI: 10.1212/wnl.0000000000011088

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