Article
Amyloid A amyloidosis in a patient with Caplan's syndrome, with special reference to genetic predisposition.
Modern rheumatology case reports - 1 Jul 2020
Nakamura Tadashi, Shiraishi Naoki, Morikami Yasuhiro, Fujii Hiromi, Yoshinaga Takeshi
Abstract excerpt
Secondary amyloid A (AA) amyloidosis, which is a disorder of protein conformation and metabolism, is an important serious complication of inflammatory diseases, especially rheumatoid arthritis (RA). AA amyloidosis develops when AA fibrils, which are derived from the acute-phase reactant, serum amyloid AA (SAA) protein, in the circulation, are deposited in organs and cause systemic organ dysfunction. Caplan's...
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