Article
lnc-HOTAIR predicts hepatocellular carcinoma in chronic hepatitis C genotype 4 following direct-acting antivirals therapy.
Molecular carcinogenesis - 1 Dec 2020
El-Khazragy Nashwa, Elshimy Amal Ali, Hassan Safaa Shawky, Shaaban Mohamed Hafez, Bayoumi Ahmed Hamed, El Magdoub Hekmat M, Ghozy Sherief, Gaballah Ahmed, Aboelhussein Marwa M, Abou Gabal Hoda H, Bannunah Azzah M, Mansy Azza El-Sayed
Abstract excerpt
Emerging hepatocellular carcinoma (HCC) has been sequentially reported in chronic hepatitis C virus (HCV) treated with direct-acting antivirals (DAAs). Homeobox transcript antisense RNA (HOTAIR), an oncogene, has been reported to be associated with cancer. We investigated the predictive value of lnc-HOTAIR for HCC surveillance in chronic HCV patients following DAAs therapy. The expression levels of lnc-HOTAIR and...
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