Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reducing misdiagnosis caused by maternal cell contamination in genetic testing for early pregnancy loss.

Systems biology in reproductive medicine - 1 Dec 2020

Volozonoka Ludmila, Gailite Linda, Perminov Dmitrijs, Kornejeva Liene, Fodina Violeta, Kempa Inga, Miskova Anna

Abstract excerpt

The analysis of products of conception (POC) is clinically important to establish the cause of early pregnancy loss. Data from such analyses can lead to specific interventions in subsequent natural or assisted conceptions. The techniques available to examine the chromosomal composition of POC have limitations and can give misleading results when maternal cell contamination (MCC) is overlooked. The aim of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Spontaneous
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diagnostic Errors

Share to Gestational Age

Share to Karyotype

Share to Karyotyping

Share to Predictive Value of Tests

Share to Specimen Handling

Source

Identifiers

PMID: 33059488
DOI: 10.1080/19396368.2020.1827081

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reducing misdiagnosis caused by maternal cell contamination in genetic testing for early pregnancy loss.PMID 33059488Read ↗

Traditional and molecular chromosomal abnormality analysis of products of conception in spontaneous and recurrent miscarriageSemantic proximity Read ↗

Optical Genome Mapping and Single Nucleotide Polymorphism Microarray: An Integrated Approach for Investigating Products of Conception.Semantic proximity Read ↗

Comparison of cytogenetics and molecular karyotyping for chromosome testing of miscarriage specimens.Semantic proximity Read ↗

Maternal plasma genome-wide cell-free DNA can detect fetal aneuploidy in early and recurrent pregnancy loss and can be used to direct further workupSemantic proximity Read ↗

Reliability of 46,XX results on miscarriage specimens: a review of 1,222 first-trimester miscarriage specimensSemantic proximity Read ↗

Salvage of fetal karyotype information from SNP array data obtained from products of conception with maternal cell contamination.Semantic proximity Read ↗

Abnormalities in spontaneous abortions detected by G-banding and chromosomal microarray analysis (CMA) at a national reference laboratorySemantic proximity Read ↗

Diagnosis of miscarriages by molecular karyotyping: Benefits and pitfallsSemantic proximity Read ↗

Genetic testing of products of conception in recurrent pregnancy loss evaluationSemantic proximity Read ↗

Implementing Prenatal Diagnosis Based on Cell-Free Fetal DNA: Accurate Identification of Factors Affecting Fetal DNA YieldSemantic proximity Read ↗

Role of genetic analysis of products of conception and PGT in managing early pregnancy lossSemantic proximity Read ↗

Traditional karyotyping vs copy number variation sequencing for detection of chromosomal abnormalities associated with spontaneous miscarriage.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.