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The combined usage of Matrine and Osthole inhibited endoplasmic reticulum apoptosis induced by PCV2

12 Oct 2020

Abstract excerpt

BACKGROUND: Porcine circovirus type 2 (PCV2) is an important and common DNA virus that infect pig and can cause immunosuppression and induce apoptosis in the infected cells. To escape the host immune system, PCV2 constantly builds up complex mechanisms or mutates genes, and that is why it is difficult to eradicate complex PCV2 infection by relying on vaccines and single compound. At present, there is few...

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PMID: 33046006
DOI: 10.1186/s12866-020-01986-2

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