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Article

IL-5 mediates monocyte phenotype and pain outcomes in fibromyalgia.

Pain - 1 May 2021

Merriwether Ericka N, Agalave Nilesh M, Dailey Dana L, Rakel Barbara A, Kolker Sandra J, Lenert Melissa E, Spagnola William H, Lu Ying, Geasland Katharine M, Allen Lee-Ann H, Burton Michael D, Sluka Kathleen A

Abstract excerpt

ABSTRACT: Fibromyalgia (FM) is characterized by widespread chronic pain, fatigue, and somatic symptoms. The influence of phenotypic changes in monocytes on symptoms associated with FM is not fully understood. The primary aim of this study was to take a comprehensive whole-body to molecular approach in characterizing relationships between monocyte phenotype and FM symptoms in relevant clinical populations....

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Identifiers

PMID: 33003107
DOI: 10.1097/j.pain.0000000000002089
PMCID: PMC7987864

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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