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SARS-CoV-2 Codon Usage Bias Downregulates Host Expressed Genes With Similar Codon Usage

20 Aug 2020

Abstract excerpt

Severe acute respiratory syndrome has spread quickly throughout the world and was declared a pandemic by the World Health Organization (WHO). The pathogenic agent is a new coronavirus (SARS-CoV-2) that infects pulmonary cells with great effectiveness. In this study we focus on the codon composition for the viral protein synthesis and its relationship with the protein synthesis of the host. Our analysis reveals...

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PMID: 32974353
DOI: 10.3389/fcell.2020.00831

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