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Article

Heritable genome-wide variation of gene expression and promoter methylation between wild and domesticated chickens.

BMC genomics - 4 Feb 2012

Nätt Daniel, Rubin Carl-Johan, Wright Dominic, Johnsson Martin, Beltéky Johan, Andersson Leif, Jensen Per

Abstract excerpt

BACKGROUND: Variations in gene expression, mediated by epigenetic mechanisms, may cause broad phenotypic effects in animals. However, it has been debated to what extent expression variation and epigenetic modifications, such as patterns of DNA methylation, are transferred across generations, and therefore it is uncertain what role epigenetic variation may play in adaptation. RESULTS: In Red Junglefowl, ancestor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22305654
DOI: 10.1186/1471-2164-13-59
PMCID: PMC3297523

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