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Article

Influence of altitude on hypertension phenotypes and responses to antihypertensive therapy: Review of the literature and design of the INTERVENCION trial.

Journal of clinical hypertension (Greenwich, Conn.) - 1 Oct 2020

Medina-Lezama Josefina, Herrera-Enriquez Karela, Narvaez-Guerra Offdan, Chirinos Julio A

Abstract excerpt

Systemic arterial hypertension constitutes the leading cause of mortality worldwide, and affects people living at different altitudes above sea level (AASL). AASL has a major impact on cardiovascular function and various biologic pathways that regulate blood pressure-related phenotypes, but whether it affects the clinical response to antihypertensive therapy is unknown. The hemodynamic adaptations observed among...

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Identifiers

PMID: 32941700
DOI: 10.1111/jch.13932
PMCID: PMC8029791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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