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Article

Excessive autophagy induces the failure of trophoblast invasion and vasculature

15 Oct 2014

Abstract excerpt

INTRODUCTION: Preeclampsia affects 5-7% of all healthy pregnancies and is characterized by hypertension and proteinuria. Although the pathogenesis of preeclampsia is still not fully understood, a failure of spiral artery transformation and aberrant placental vasculature are considered to be facets of this disease. Studies have also implicated increased autophagic activity. In this study, we investigated whether...

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Share to Maternal and fetal healthcare
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PMID: 25318653
DOI: 10.1097/hjh.0000000000000366

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