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Article

Analyzing Gene Expression Profiles from Ataxia and Spasticity Phenotypes to Reveal Spastic Ataxia Related Pathways.

International journal of molecular sciences - 14 Sept 2020

Kakouri Andrea C, Votsi Christina, Tomazou Marios, Minadakis George, Karatzas Evangelos, Christodoulou Kyproula, Spyrou George M

Abstract excerpt

Spastic ataxia (SA) is a group of rare neurodegenerative diseases, characterized by mixed features of generalized ataxia and spasticity. The pathogenetic mechanisms that drive the development of the majority of these diseases remain unclear, although a number of studies have highlighted the involvement of mitochondrial and lipid metabolism, as well as calcium signaling. Our group has previously published the GBA2...

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Identifiers

PMID: 32937819
DOI: 10.3390/ijms21186722
PMCID: PMC7555177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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