Article
Conventional Dendritic Cells and Slan+ Monocytes During HIV-2 Infection.
Frontiers in immunology - 1 Jan 2020
Iannetta Marco, Isnard Stéphane, Manuzak Jennifer, Guillerme Jean-Baptiste, Notin Mathilde, Bailly Karine, Andrieu Muriel, Amraoui Sonia, Vimeux Lene, Figueiredo Suzanne, Charmeteau-de Muylder Bénédicte, Vaton Laura, Hatton Etienne X, Samri Assia, Autran Brigitte, Thiébaut Rodolphe, Chaghil Nathalie, Glohi David, Charpentier Charlotte, Descamps Diane, Brun-Vézinet Françoise, Matheron Sophie, Cheynier Remi, Hosmalin Anne
Abstract excerpt
HIV-2 infection is characterized by low viremia and slow disease progression as compared to HIV-1 infection. Circulating CD14++CD16+ monocytes were found to accumulate and CD11c+ conventional dendritic cells (cDC) to be depleted in a Portuguese cohort of people living with HIV-2 (PLWHIV-2), compared to blood bank healthy donors (HD). We studied more precisely classical monocytes; CD16+ inflammatory (intermediate,...
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