Article
Nilotinib-induced liver injury: A case report.
Medicine - 4 Sept 2020
Tan Youwen, Ye Yun, Zhou Xingbei
Abstract excerpt
INTRODUCTION: Nilotinib is a selective inhibitor of the BCR-ABL tyrosine kinase receptor and is used in the management of chronic myelogenous leukemia (CML). Nilotinib therapy at high doses is associated with elevated serum bilirubin levels. If the serum bilirubin level exceeds 3 times the upper limit of normal, the recommendation is to either adjust nilotinib dosage or temporarily discontinue the treatment....
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