Article
Extended application of genomic selection to screen multiomics data for prognostic signatures of prostate cancer.
Briefings in bioinformatics - 20 May 2021
Li Ruidong, Wang Shibo, Cui Yanru, Qu Han, Chater John M, Zhang Le, Wei Julong, Wang Meiyue, Xu Yang, Yu Lei, Lu Jianming, Feng Yuanfa, Zhou Rui, Huang Yuhan, Ma Renyuan, Zhu Jianguo, Zhong Weide, Jia Zhenyu
Abstract excerpt
Prognostic tests using expression profiles of several dozen genes help provide treatment choices for prostate cancer (PCa). However, these tests require improvement to meet the clinical need for resolving overtreatment, which continues to be a pervasive problem in PCa management. Genomic selection (GS) methodology, which utilizes whole-genome markers to predict agronomic traits, was adopted in this study for PCa...
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