Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A protein interaction map identifies existing drugs targeting SARS-CoV-2

3 Sept 2020

Abstract excerpt

BACKGROUND: Severe acute respiratory syndrome coronavirus (SARS-CoV-2), an emerging Betacoronavirus, is the causative agent of COVID-19. Angiotensin converting enzyme 2 (ACE2), being the main cell receptor of SARS-CoV-2, plays a role in the entry of the virus into the cell. Currently, there are neither specific antiviral drugs for the treatment or preventive drugs such as vaccines. METHODS: We proposed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioinformatics and Genomic Networks
Share to Computational Drug Discovery Methods
Share to COVID-19 Clinical Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32883368
DOI: 10.1186/s40360-020-00444-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A protein interaction map identifies existing drugs targeting SARS-CoV-2PMID 32883368Read ↗

A protein interaction map identifies existing drugs targeting SARS-CoV-2Semantic proximity Read ↗

Pathways and microRNAs bioinformatics analyses identifying possible existing therapeutics for COVID-19 treatmentSemantic proximity Read ↗

Pathways and microRNAs bioinformatics analyses identifying possible existing therapeutics for COVID-19 treatmentSemantic proximity Read ↗

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expressionSemantic proximity Read ↗

Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; An updated reviewSemantic proximity Read ↗

Discovery of potential drugs for COVID-19 based on the connectivity mapSemantic proximity Read ↗

Identification of potential inhibitors of SARS-CoV-2 S protein–ACE2 interaction by in silico drug repurposingSemantic proximity Read ↗

ACE2 Co-Evolutionary Pattern Suggests Targets for Pharmaceutical Intervention in the COVID-19 PandemicSemantic proximity Read ↗

Angiotensin Converting Enzyme 2 in Coronavirus Disease (COVID-19): Evidence from Bioinformatics AnalysisSemantic proximity Read ↗

Potential Drugs Against COVID-19 Revealed by Gene Expression Profile, Molecular Docking and Molecular Dynamic SimulationSemantic proximity Read ↗

Drug Repurposing for Covid-19: Discovery of Potential Small-Molecule Inhibitors of Spike Protein-ACE2 Receptor Interaction Through Virtual Screening and Consensus ScoringSemantic proximity Read ↗

ACE2 Netlas: In-silico functional characterization and drug-gene interactions of <i>ACE2</i> gene network to understand its potential involvement in COVID-19 susceptibilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.