Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapy in Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa.

Molecular therapy : the journal of the American Society of Gene Therapy - 7 Oct 2020

Meng Da, Ragi Sara D, Tsang Stephen H

Abstract excerpt

Rhodopsin-mediated autosomal dominant retinitis pigmentosa (RHO-adRP) is a hereditary degenerative disorder in which mutations in the gene encoding RHO, the light-sensitive G protein-coupled receptor involved in phototransduction in rods, lead to progressive loss of rods and subsequently cones in the retina. Clinical phenotypes are diverse, ranging from mild night blindness to severe visual impairments. There is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Management
Share to Gene Editing
Share to Genes, Dominant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Therapy

Share to Retinitis Pigmentosa

Share to Rhodopsin

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 32882181
DOI: 10.1016/j.ymthe.2020.08.012
PMCID: PMC7545001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapy in Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa.PMID 32882181Read ↗

Genetic treatment for autosomal dominant inherited retinal dystrophies: approaches, challenges and targeted genotypes.Semantic proximity Read ↗

Progress in Gene Therapy for Rhodopsin Autosomal Dominant Retinitis Pigmentosa.Semantic proximity Read ↗

Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variationSemantic proximity Read ↗

Rhodopsin-associated retinal dystrophy: Disease mechanisms and therapeutic strategiesSemantic proximity Read ↗

Disease modeling and pharmacological rescue of autosomal dominant Retinitis Pigmentosa associated with <i>RHO</i> copy number variationSemantic proximity Read ↗

CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model.Semantic proximity Read ↗

Knockout and Replacement Gene Surgery to Treat Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa.Semantic proximity Read ↗

Gene Therapy for Retinitis Pigmentosa: Current Challenges and New Progress.Semantic proximity Read ↗

RHO1-2 meganuclease gene editing targets human P23H rhodopsin-induced retinitis pigmentosa to rejuvenate rods and maintain conesSemantic proximity Read ↗

Allele-specific gene-editing approach for vision loss restoration in RHO-associated retinitis pigmentosa.Semantic proximity Read ↗

CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa.Semantic proximity Read ↗

Molecular Strategies for RPGR Gene TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.