Article
LRFN2 gene variant rs2494938 provides susceptibility to esophageal cancer in the population of Jammu and Kashmir.
Journal of cancer research and therapeutics - 1 Dec 2020
Shah Ruchi, Sharma Varun, Singh Hemender, Sharma Indu, Bhat Gulzar Ahmed, Shah Idrees Ayoub, Iqbal Beenish, Rafiq Rumisa, Nissa Najma, Muzaffar Mansha, Rasool Malik Tariq, Lone Ghulam Nabi, Kaul Sandeep, Lone Mohd Maqbool, Rai Ekta, Dar Nazir Ahmed, Sharma Swarkar
Abstract excerpt
BACKGROUND: Leucine-rich repeat and fibronectin type 2 gene (LRFN2) variant rs2494938 has recently been found associated with esophageal cancer in a genome-wide association study in an Asian population. However, this association has not been replicated in any Indian population despite high incidence of the disease. MATERIALS AND METHODS: In the present case-control study, 166 cases and 459 controls were included....
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