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Targeted Metagenomics for Clinical Detection and Discovery of Bacterial Tick-Borne Pathogens

1 Sept 2020

Abstract excerpt

Tick-borne diseases, due to a diversity of bacterial pathogens, represent a significant and increasing public health threat throughout the Northern Hemisphere. A high-throughput 16S V1-V2 rRNA gene-based metagenomics assay was developed and evaluated using >13,000 residual samples from patients suspected of having tick-borne illness and >1,000 controls. Taxonomic predictions for tick-borne bacteria were...

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PMID: 32878950
DOI: 10.1128/jcm.00147-20

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