Article
Pretreatment structural and arterial spin labeling MRI is predictive for p53 mutation in high-grade gliomas.
The British journal of radiology - 1 Nov 2020
Mao Jiaji, Deng Dabiao, Yang Zehong, Wang Wensheng, Cao Minghui, Huang Yun, Shen Jun
Abstract excerpt
OBJECTIVES: To determine the performance of pretreatment structural and arterial spin labelling (ASL) MRI in predicting p53 mutation in patients with high-grade gliomas (HGGs). METHODS: Pre-treatment structural and ASL MRI were performed in 57 patients with histologically confirmed HGGs and information of p53 status. Whole-lesion histogram analysis of cerebral blood flow (CBF) images of the enhancing tumour and...
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