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Characterization of accessory genes in coronavirus genomes

27 Aug 2020

Abstract excerpt

BACKGROUND: The Covid19 infection is caused by the SARS-CoV-2 virus, a novel member of the coronavirus (CoV) family. CoV genomes code for a ORF1a / ORF1ab polyprotein and four structural proteins widely studied as major drug targets. The genomes also contain a variable number of open reading frames (ORFs) coding for accessory proteins that are not essential for virus replication, but appear to have a role in...

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PMID: 32854725
DOI: 10.1186/s12985-020-01402-1

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