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Article

Host Polymorphisms May Impact SARS-CoV-2 Infectivity.

Trends in genetics : TIG - 1 Nov 2020

Brest Patrick, Refae Sadal, Mograbi Baharia, Hofman Paul, Milano Gerard

Abstract excerpt

Based on a broad public database compilation, we support the hypothesis that germinal polymorphisms may regulate the expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular target itself and proteases controlling the process of its shedding or, conversely, its internalization. Consequently, a genetic influence on individual susceptibility to coronavirus disease 2019 (COVID-19)...

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Identifiers

PMID: 32828550
DOI: 10.1016/j.tig.2020.08.003
PMCID: PMC7416730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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