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Article

Tick-Borne Encephalitis Virus Adaptation in Different Host Environments and Existence of Quasispecies.

Viruses - 18 Aug 2020

Helmová Renata, Hönig Václav, Tykalová Hana, Palus Martin, Bell-Sakyi Lesley, Grubhoffer Libor

Abstract excerpt

A highly virulent strain (Hypr) of tick-borne encephalitis virus (TBEV) was serially subcultured in the mammalian porcine kidney stable (PS) and Ixodes ricinus tick (IRE/CTVM19) cell lines, producing three viral variants. These variants exhibited distinct plaque sizes and virulence in a mouse model. Comparing the full-genome sequences of all variants, several nucleotide changes were identified in different...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32824843
DOI: 10.3390/v12080902
PMCID: PMC7472235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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