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Neuroimaging PheWAS (Phenome-Wide Association Study): A Free Cloud-Computing Platform for Big-Data, Brain-Wide Imaging Association Studies.

Neuroinformatics - 1 Apr 2021

Zhao Lu, Batta Ishaan, Matloff William, O'Driscoll Caroline, Hobel Samuel, Toga Arthur W

Abstract excerpt

Large-scale, case-control genome-wide association studies (GWASs) have revealed genetic variations associated with diverse neurological and psychiatric disorders. Recent advances in neuroimaging and genomic databases of large healthy and diseased cohorts have empowered studies to characterize effects of the discovered genetic factors on brain structure and function, implicating neural pathways and genetic...

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Identifiers

PMID: 32822005
DOI: 10.1007/s12021-020-09486-4
PMCID: PMC7897334

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