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Article

High genetic burden of type 2 diabetes can promote the high prevalence of disease: a longitudinal cohort study in Iran.

Scientific reports - 19 Aug 2020

Moazzam-Jazi Maryam, Najd Hassan Bonab Leila, Zahedi Asiyeh Sadat, Daneshpour Maryam S

Abstract excerpt

Type 2 diabetes (T2D) is emerging as one of the serious public health issues in both developed and developing counties. Here, we surveyed the worldwide population differentiation in T2D-associated variants and assessed the genetic burden of the disease in an ongoing Tehran Cardio-Metabolic Genetic Study (TCGS) cohort represented the Iranian population. We found multiple SNPs that were significantly depleted or...

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Identifiers

PMID: 32814780
DOI: 10.1038/s41598-020-70725-4
PMCID: PMC7438483

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