Article
Factors associated with use of hormone therapy after preventive oophorectomy in BRCA mutation carriers.
Menopause (New York, N.Y.) - 1 Dec 2020
Mejia-Gomez Javier, Gronwald Jacek, Senter Leigha, Karlan Beth Y, Tung Nadine, Wolfman Wendy, Demsky Rochelle, Sun Ping, Narod Steven A, Kotsopoulos Joanne
Abstract excerpt
OBJECTIVE: Bilateral salpingo-oophorectomy (oophorectomy) is recommended to women with a germline BRCA1 or BRCA2 mutation before natural menopause to prevent ovarian and fallopian tube cancer. The adverse effects of early surgical menopause are well established. Although many of the side effects can be ameliorated by the use of hormone therapy (HT); use of HT in this group of predominantly young patients remains...
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