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Article

Relationships between increased circulating YKL-40, IL-6 and TNF-α levels and phenotypes and disease activity of primary Sjögren's syndrome.

International immunopharmacology - 1 Nov 2020

Chen Caiqun, Liang Yan, Zhang Zhiyu, Zhang Zhencheng, Yang Zaixing

Abstract excerpt

BACKGROUND: There is now no single score or marker useful for evaluating disease activity of primary Sjögren's syndrome (pSS). This study was designed to explore the associations of circulating YKL-40, interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) with systemic activity and phenotypes of pSS. METHODS: This study included 58 pSS patients and 30 healthy controls (HC). The sera were measured by multiplex...

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PMID: 32791244
DOI: 10.1016/j.intimp.2020.106878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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