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Advanced Glycation End Products Enhance Biofilm Formation by Promoting Extracellular DNA Release Through sigB Upregulation in Staphylococcus aureus

14 Jul 2020

Abstract excerpt

Bacterial biofilms do serious harm to the diabetic foot ulcer (DFU) because they play a crucial role in infection invasion and spread. Staphylococcus aureus (S. aureus), the predominant Gram-positive bacteria in diabetic foot infection, is often associated with colonization and biofilm formation. Through biofilm formation tests in vitro, we observed that S. aureus bacteria isolated from DFU wounds were more prone...

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PMID: 32765439
DOI: 10.3389/fmicb.2020.01479

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