Article
Breast MRI texture analysis for prediction of BRCA-associated genetic risk.
BMC medical imaging - 29 Jul 2020
Vasileiou Georgia, Costa Maria J, Long Christopher, Wetzler Iris R, Hoyer Juliane, Kraus Cornelia, Popp Bernt, Emons Julius, Wunderle Marius, Wenkel Evelyn, Uder Michael, Beckmann Matthias W, Jud Sebastian M, Fasching Peter A, Cavallaro Alexander, Reis André, Hammon Matthias
Abstract excerpt
BACKGROUND: BRCA1/2 deleterious variants account for most of the hereditary breast and ovarian cancer cases. Prediction models and guidelines for the assessment of genetic risk rely heavily on criteria with high variability such as family cancer history. Here we investigated the efficacy of MRI (magnetic resonance imaging) texture features as a predictor for BRCA mutation status. METHODS: A total of 41 female...
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