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Article

Bioinformatic identification of key pathways, hub genes, and microbiota for therapeutic intervention in Helicobacter pylori infection.

Journal of cellular physiology - 1 Feb 2021

Chen Zhenhui, Chen Huijuan, Yu Lu, Xin Hongjie, Kong Jingjing, Bai Yang, Zeng Weisen, Zhang Jumei, Wu Qingping, Fan Hongying

Abstract excerpt

The pathogenic mechanisms of Helicobacter pylori infection remain to be defined, and potential interventional microbiota are just beginning to be identified. In this study, gene-set enrichment analysis (GSEA) was used to integrate three H. pylori infection microarray data sets from the gene expression omnibus database and identified ten hallmark gene sets and 35 Kyoto encyclopedia of genes and genomes (KEGG)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32710499
DOI: 10.1002/jcp.29925

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